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Immunization with inactivated whole virus particle influenza virus vaccines improves the humoral response landscape in cynomolgus macaques

Although antibody-inducing split virus vaccines (SV) are currently the most effective way to combat seasonal influenza, their efficacy can be modest, especially in immunologically-naïve individuals. We investigated immune responses towards inactivated whole influenza virus particle vaccine (WPV) for...

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Detalles Bibliográficos
Autores principales: Chua, Brendon Y., Sekiya, Toshiki, Koutsakos, Marios, Nomura, Naoki, Rowntree, Louise C., Nguyen, Thi H. O., McQuilten, Hayley A., Ohno, Marumi, Ohara, Yuki, Nishimura, Tomohiro, Endo, Masafumi, Itoh, Yasushi, Habel, Jennifer R., Selva, Kevin J., Wheatley, Adam K., Wines, Bruce D., Hogarth, P. Mark, Kent, Stephen J., Chung, Amy W., Jackson, David C., Brown, Lorena E., Shingai, Masashi, Kedzierska, Katherine, Kida, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581423/
https://www.ncbi.nlm.nih.gov/pubmed/36206307
http://dx.doi.org/10.1371/journal.ppat.1010891