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Understanding molecular mechanisms and predicting phenotypic effects of pathogenic tubulin mutations
Cells rely heavily on microtubules for several processes, including cell division and molecular trafficking. Mutations in the different tubulin-α and -β proteins that comprise microtubules have been associated with various diseases and are often dominant, sporadic and congenital. While the earliest...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581425/ https://www.ncbi.nlm.nih.gov/pubmed/36206299 http://dx.doi.org/10.1371/journal.pcbi.1010611 |