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Identification of risk genes for Alzheimer’s disease by gene embedding

Most disease-gene association methods do not account for gene-gene interactions, even though these play a crucial role in complex, polygenic diseases like Alzheimer’s disease (AD). To discover new genes whose interactions may contribute to pathology, we introduce GeneEMBED. This approach compares th...

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Detalles Bibliográficos
Autores principales:	Lagisetty, Yashwanth, Bourquard, Thomas, Al-Ramahi, Ismael, Mangleburg, Carl Grant, Mota, Samantha, Soleimani, Shirin, Shulman, Joshua M., Botas, Juan, Lee, Kwanghyuk, Lichtarge, Olivier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581494/ https://www.ncbi.nlm.nih.gov/pubmed/36268052 http://dx.doi.org/10.1016/j.xgen.2022.100162

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