A Machine Learning Workflow of Multiplexed Immunofluorescence Images to Interrogate Activator and Tolerogenic Profiles of Conventional Type 1 Dendritic Cells Infiltrating Melanomas of Disease-Free and Metastatic Patients

Melanoma is the deadliest form of skin cancer. Due to its high mutation rates, melanoma is a convenient model to study antitumor immune responses. Dendritic cells (DCs) play a key role in activating cytotoxic CD8(+) T lymphocytes and directing them to kill tumor cells. Although there is evidence tha...

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Detalles Bibliográficos
Autores principales: De León Rodríguez, Saraí G., Hernández Herrera, Paúl, Aguilar Flores, Cristina, Pérez Koldenkova, Vadim, Guerrero, Adán, Mantilla, Alejandra, Fuentes-Pananá, Ezequiel M., Wood, Christopher, Bonifaz, Laura C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581597/
https://www.ncbi.nlm.nih.gov/pubmed/36276271
http://dx.doi.org/10.1155/2022/9775736

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