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Effects of Remimazolam Combined with Esketamine Anesthesia on Circulatory and Respiratory Function during Painless Gastroenteroscopy
OBJECTIVE: To investigate the effect of applying remimazolam combined with esketamine for anesthesia in painless gastroenteroscopy on patients' circulatory and respiratory function. METHOD: In this study, 106 patients who had undergone painless gastroenteroscopy in Xinjiang Production and Const...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581615/ https://www.ncbi.nlm.nih.gov/pubmed/36304777 http://dx.doi.org/10.1155/2022/1079099 |
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author | Lu, Cheng Ren, Jun Guo, Xin Qian, Jiang |
author_facet | Lu, Cheng Ren, Jun Guo, Xin Qian, Jiang |
author_sort | Lu, Cheng |
collection | PubMed |
description | OBJECTIVE: To investigate the effect of applying remimazolam combined with esketamine for anesthesia in painless gastroenteroscopy on patients' circulatory and respiratory function. METHOD: In this study, 106 patients who had undergone painless gastroenteroscopy in Xinjiang Production and Construction Corps (XPCC) Hospital between July 2021 and January 2022 were selected as study subjects, which were grouped according to the anesthetic drugs used in the surgery and divided into control group (n = 53 cases) and observation group (n = 53 cases), while those who were anesthetized with propofol + sufentanil during the operation were the control group and those who were anesthetized with remimazolam + esketamine were the observation group. To compare the induction time of anesthesia, patient awakening and recovery time of orientation, circulatory and respiratory function, intraoperative adverse effects, and postoperative complications in the two study groups. RESULTS: There was no statistical difference in induction of anesthesia, patient awakening, and recovery time of orientation between the two groups (P > 0.05) and no statistical difference in postoperative complications (P > 0.05). The observation group had a better occurrence of local pain at the injection site, circulatory and respiratory function of patients after anesthesia, and intraoperative adverse reactions than the control group (P < 0.05). CONCLUSION: Remimazolam combined with esketamine anesthesia has the same advantages of rapid awakening compared with propofol anesthesia. Moreover, it has fewer side effects on patients' circulatory and respiratory functions with fewer adverse effects, as a suitable anesthetic method for painless gastroenteroscopy. |
format | Online Article Text |
id | pubmed-9581615 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-95816152022-10-26 Effects of Remimazolam Combined with Esketamine Anesthesia on Circulatory and Respiratory Function during Painless Gastroenteroscopy Lu, Cheng Ren, Jun Guo, Xin Qian, Jiang Contrast Media Mol Imaging Research Article OBJECTIVE: To investigate the effect of applying remimazolam combined with esketamine for anesthesia in painless gastroenteroscopy on patients' circulatory and respiratory function. METHOD: In this study, 106 patients who had undergone painless gastroenteroscopy in Xinjiang Production and Construction Corps (XPCC) Hospital between July 2021 and January 2022 were selected as study subjects, which were grouped according to the anesthetic drugs used in the surgery and divided into control group (n = 53 cases) and observation group (n = 53 cases), while those who were anesthetized with propofol + sufentanil during the operation were the control group and those who were anesthetized with remimazolam + esketamine were the observation group. To compare the induction time of anesthesia, patient awakening and recovery time of orientation, circulatory and respiratory function, intraoperative adverse effects, and postoperative complications in the two study groups. RESULTS: There was no statistical difference in induction of anesthesia, patient awakening, and recovery time of orientation between the two groups (P > 0.05) and no statistical difference in postoperative complications (P > 0.05). The observation group had a better occurrence of local pain at the injection site, circulatory and respiratory function of patients after anesthesia, and intraoperative adverse reactions than the control group (P < 0.05). CONCLUSION: Remimazolam combined with esketamine anesthesia has the same advantages of rapid awakening compared with propofol anesthesia. Moreover, it has fewer side effects on patients' circulatory and respiratory functions with fewer adverse effects, as a suitable anesthetic method for painless gastroenteroscopy. Hindawi 2022-10-12 /pmc/articles/PMC9581615/ /pubmed/36304777 http://dx.doi.org/10.1155/2022/1079099 Text en Copyright © 2022 Cheng Lu et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Lu, Cheng Ren, Jun Guo, Xin Qian, Jiang Effects of Remimazolam Combined with Esketamine Anesthesia on Circulatory and Respiratory Function during Painless Gastroenteroscopy |
title | Effects of Remimazolam Combined with Esketamine Anesthesia on Circulatory and Respiratory Function during Painless Gastroenteroscopy |
title_full | Effects of Remimazolam Combined with Esketamine Anesthesia on Circulatory and Respiratory Function during Painless Gastroenteroscopy |
title_fullStr | Effects of Remimazolam Combined with Esketamine Anesthesia on Circulatory and Respiratory Function during Painless Gastroenteroscopy |
title_full_unstemmed | Effects of Remimazolam Combined with Esketamine Anesthesia on Circulatory and Respiratory Function during Painless Gastroenteroscopy |
title_short | Effects of Remimazolam Combined with Esketamine Anesthesia on Circulatory and Respiratory Function during Painless Gastroenteroscopy |
title_sort | effects of remimazolam combined with esketamine anesthesia on circulatory and respiratory function during painless gastroenteroscopy |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581615/ https://www.ncbi.nlm.nih.gov/pubmed/36304777 http://dx.doi.org/10.1155/2022/1079099 |
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