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Outcomes of Human Papilloma Virus Vaccination in a Private Women Health Clinic in Lebanon

OBJECTIVES: The study aims to report on the feasibility and associated adverse events of HPV-Vaccination (HPVV) in a private clinic setting in Lebanon and, when available, the results of subsequent cervical cancer screening. METHODS: Opportunistic HPV vaccination is offered at the Women's Healt...

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Autores principales: Seoud, Muhieddine, Jaafar, Iman, Ghanem, Rayan, Soubhieh, Christiane, Adra, Abdallah, Nassar, Anwar, Khalil, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581706/
https://www.ncbi.nlm.nih.gov/pubmed/36274656
http://dx.doi.org/10.1155/2022/7342061
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author Seoud, Muhieddine
Jaafar, Iman
Ghanem, Rayan
Soubhieh, Christiane
Adra, Abdallah
Nassar, Anwar
Khalil, Ali
author_facet Seoud, Muhieddine
Jaafar, Iman
Ghanem, Rayan
Soubhieh, Christiane
Adra, Abdallah
Nassar, Anwar
Khalil, Ali
author_sort Seoud, Muhieddine
collection PubMed
description OBJECTIVES: The study aims to report on the feasibility and associated adverse events of HPV-Vaccination (HPVV) in a private clinic setting in Lebanon and, when available, the results of subsequent cervical cancer screening. METHODS: Opportunistic HPV vaccination is offered at the Women's Health Center of the AUBMC. We retrospectively reviewed the patients' demographic data, the incidence of adverse events, and their cytological screening. RESULTS: A cohort of healthy women (n = 1013) aged 26.2 years (12–54 years) were opportunistically vaccinated with one of two HPV vaccines; 845 (83.4%) received the quadrivalent vaccine (Q4V), and 151 (14.1%) received the bivalent vaccine (B2V). The majority (75.8%) received three doses while 16% received two doses. Out of these women, 26.3% (267) became sexually active postvaccination (NS2), whereas 17% (174) were sexually active prior to vaccination (SA) and the rest 57% (572) reported no sexual activity (NS1). Among the SA group, 26% (46/147) presented with abnormal cytology at time of vaccination. As for the NS2 women, 5% (14/267) had subsequently abnormal screening within 37 (12–103) months following vaccination. CONCLUSIONS: In this observational study, we report the successful introduction of HPVV with negligible adverse events. The incidence of abnormal cervical cytology was low among our patients.
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spelling pubmed-95817062022-10-20 Outcomes of Human Papilloma Virus Vaccination in a Private Women Health Clinic in Lebanon Seoud, Muhieddine Jaafar, Iman Ghanem, Rayan Soubhieh, Christiane Adra, Abdallah Nassar, Anwar Khalil, Ali Obstet Gynecol Int Research Article OBJECTIVES: The study aims to report on the feasibility and associated adverse events of HPV-Vaccination (HPVV) in a private clinic setting in Lebanon and, when available, the results of subsequent cervical cancer screening. METHODS: Opportunistic HPV vaccination is offered at the Women's Health Center of the AUBMC. We retrospectively reviewed the patients' demographic data, the incidence of adverse events, and their cytological screening. RESULTS: A cohort of healthy women (n = 1013) aged 26.2 years (12–54 years) were opportunistically vaccinated with one of two HPV vaccines; 845 (83.4%) received the quadrivalent vaccine (Q4V), and 151 (14.1%) received the bivalent vaccine (B2V). The majority (75.8%) received three doses while 16% received two doses. Out of these women, 26.3% (267) became sexually active postvaccination (NS2), whereas 17% (174) were sexually active prior to vaccination (SA) and the rest 57% (572) reported no sexual activity (NS1). Among the SA group, 26% (46/147) presented with abnormal cytology at time of vaccination. As for the NS2 women, 5% (14/267) had subsequently abnormal screening within 37 (12–103) months following vaccination. CONCLUSIONS: In this observational study, we report the successful introduction of HPVV with negligible adverse events. The incidence of abnormal cervical cytology was low among our patients. Hindawi 2022-10-12 /pmc/articles/PMC9581706/ /pubmed/36274656 http://dx.doi.org/10.1155/2022/7342061 Text en Copyright © 2022 Muhieddine Seoud et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Seoud, Muhieddine
Jaafar, Iman
Ghanem, Rayan
Soubhieh, Christiane
Adra, Abdallah
Nassar, Anwar
Khalil, Ali
Outcomes of Human Papilloma Virus Vaccination in a Private Women Health Clinic in Lebanon
title Outcomes of Human Papilloma Virus Vaccination in a Private Women Health Clinic in Lebanon
title_full Outcomes of Human Papilloma Virus Vaccination in a Private Women Health Clinic in Lebanon
title_fullStr Outcomes of Human Papilloma Virus Vaccination in a Private Women Health Clinic in Lebanon
title_full_unstemmed Outcomes of Human Papilloma Virus Vaccination in a Private Women Health Clinic in Lebanon
title_short Outcomes of Human Papilloma Virus Vaccination in a Private Women Health Clinic in Lebanon
title_sort outcomes of human papilloma virus vaccination in a private women health clinic in lebanon
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581706/
https://www.ncbi.nlm.nih.gov/pubmed/36274656
http://dx.doi.org/10.1155/2022/7342061
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