Sublinear scaling of the cellular proteome with ploidy

Ploidy changes are frequent in nature and contribute to evolution, functional specialization and tumorigenesis. Analysis of model organisms of different ploidies revealed that increased ploidy leads to an increase in cell and nuclear volume, reduced proliferation, metabolic changes, lower fitness, a...

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Detalles Bibliográficos
Autores principales: Yahya, G., Menges, P., Amponsah, P. S., Ngandiri, D. A., Schulz, D., Wallek, A., Kulak, N., Mann, M., Cramer, P., Savage, V., Räschle, M., Storchova, Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581932/
https://www.ncbi.nlm.nih.gov/pubmed/36261409
http://dx.doi.org/10.1038/s41467-022-33904-7

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