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Combination venetoclax and selinexor effective in relapsed refractory multiple myeloma with translocation t(11;14)
Patients with multiple myeloma-bearing translocation t(11;14) have recently been shown to benefit from the apoptosis-inducing drug venetoclax; however, the drug lacks FDA approval in multiple myeloma thus far due to a potential safety signal in the overall patient population. Selinexor is an inhibit...
Autores principales: | Nguyen, Nina, Chaudhry, Sana, Totiger, Tulasigeri M., Diaz, Robert, Roberts, Evan, Montoya, Skye, Pardo, Gabriel, Pardo, Alejandro, Afaghani, Jumana, Affer, Maurizio, Jahn, Jacob, Bradley, Terrence, Maura, Francesco, Kazandjian, Dickran, Bilbao, Daniel, Chapman, Jennifer, Landgren, Ola, Hoffman, James, Taylor, Justin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581939/ https://www.ncbi.nlm.nih.gov/pubmed/36261486 http://dx.doi.org/10.1038/s41698-022-00315-2 |
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