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Phacoemulsification combined with micropulse cyclodiode laser in glaucoma patients: efficacy and safety

OBJECTIVE: To evaluate the safety and efficacy of phacoemulsification combined with Micropulse transscleral cyclophotocoagulation (MP-TSCPC) in glaucoma patients. METHODS: This is a retrospective case-note review. The participants were adult patients with diagnoses of glaucoma and cataract who requi...

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Autores principales: Daas, Arij, Sherman, Thomas, Danieliute, Lina, Goyal, Saurabh, Amon, Andrew, Rodrigues, Ian, Karimi, Ayesha, Lim, Kin Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581962/
https://www.ncbi.nlm.nih.gov/pubmed/34743209
http://dx.doi.org/10.1038/s41433-021-01826-1
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author Daas, Arij
Sherman, Thomas
Danieliute, Lina
Goyal, Saurabh
Amon, Andrew
Rodrigues, Ian
Karimi, Ayesha
Lim, Kin Sheng
author_facet Daas, Arij
Sherman, Thomas
Danieliute, Lina
Goyal, Saurabh
Amon, Andrew
Rodrigues, Ian
Karimi, Ayesha
Lim, Kin Sheng
author_sort Daas, Arij
collection PubMed
description OBJECTIVE: To evaluate the safety and efficacy of phacoemulsification combined with Micropulse transscleral cyclophotocoagulation (MP-TSCPC) in glaucoma patients. METHODS: This is a retrospective case-note review. The participants were adult patients with diagnoses of glaucoma and cataract who required a further reduction in IOP or a reduction in the number of glaucoma drops. All consecutive patients who underwent cataract surgery (CS) combined with MP-TSCPC laser between October 2018 and July 2019 were included in the study. The effect on visual acuity (VA), intraocular pressure (IOP) and number of anti-glaucoma drops were evaluated at 6 and 12 months in addition to any complications that occurred during any time point of the study. RESULTS: 42 eyes were included in the study. Mean IOP was reduced from 19.5 ± 5.4 mmHg by 22.5% to 15.1 ± 4.6 at 6 months post-operatively and by 19.5% to 15 ± 6.6 mm Hg at 12 months (p < 0.001 at both time points). The number of anti-glaucoma medications also reduced significantly from 2.8 ± 1.3 to 1.6 ± 1.2 at 6 months and to 2.2 ± 1.3 at 12 months (p < 0.001 at both time points). The success rate was 56% at 6 months and 54% at 12 months. 54.7% of our patients who completed 12 months follow up had an improvement or unchanged vision at the last visits. CONCLUSION: This is the first study evaluating the effect of cataract surgery combined with MP-TSCPC in glaucoma patients. We demonstrated that this led to a reduction in IOP and the number of anti-glaucoma medications at 6 and 12-month postoperatively. The majority of patients had either stable or better vision at 12 months follow-up.
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spelling pubmed-95819622022-10-21 Phacoemulsification combined with micropulse cyclodiode laser in glaucoma patients: efficacy and safety Daas, Arij Sherman, Thomas Danieliute, Lina Goyal, Saurabh Amon, Andrew Rodrigues, Ian Karimi, Ayesha Lim, Kin Sheng Eye (Lond) Article OBJECTIVE: To evaluate the safety and efficacy of phacoemulsification combined with Micropulse transscleral cyclophotocoagulation (MP-TSCPC) in glaucoma patients. METHODS: This is a retrospective case-note review. The participants were adult patients with diagnoses of glaucoma and cataract who required a further reduction in IOP or a reduction in the number of glaucoma drops. All consecutive patients who underwent cataract surgery (CS) combined with MP-TSCPC laser between October 2018 and July 2019 were included in the study. The effect on visual acuity (VA), intraocular pressure (IOP) and number of anti-glaucoma drops were evaluated at 6 and 12 months in addition to any complications that occurred during any time point of the study. RESULTS: 42 eyes were included in the study. Mean IOP was reduced from 19.5 ± 5.4 mmHg by 22.5% to 15.1 ± 4.6 at 6 months post-operatively and by 19.5% to 15 ± 6.6 mm Hg at 12 months (p < 0.001 at both time points). The number of anti-glaucoma medications also reduced significantly from 2.8 ± 1.3 to 1.6 ± 1.2 at 6 months and to 2.2 ± 1.3 at 12 months (p < 0.001 at both time points). The success rate was 56% at 6 months and 54% at 12 months. 54.7% of our patients who completed 12 months follow up had an improvement or unchanged vision at the last visits. CONCLUSION: This is the first study evaluating the effect of cataract surgery combined with MP-TSCPC in glaucoma patients. We demonstrated that this led to a reduction in IOP and the number of anti-glaucoma medications at 6 and 12-month postoperatively. The majority of patients had either stable or better vision at 12 months follow-up. Nature Publishing Group UK 2021-11-06 2022-11 /pmc/articles/PMC9581962/ /pubmed/34743209 http://dx.doi.org/10.1038/s41433-021-01826-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Daas, Arij
Sherman, Thomas
Danieliute, Lina
Goyal, Saurabh
Amon, Andrew
Rodrigues, Ian
Karimi, Ayesha
Lim, Kin Sheng
Phacoemulsification combined with micropulse cyclodiode laser in glaucoma patients: efficacy and safety
title Phacoemulsification combined with micropulse cyclodiode laser in glaucoma patients: efficacy and safety
title_full Phacoemulsification combined with micropulse cyclodiode laser in glaucoma patients: efficacy and safety
title_fullStr Phacoemulsification combined with micropulse cyclodiode laser in glaucoma patients: efficacy and safety
title_full_unstemmed Phacoemulsification combined with micropulse cyclodiode laser in glaucoma patients: efficacy and safety
title_short Phacoemulsification combined with micropulse cyclodiode laser in glaucoma patients: efficacy and safety
title_sort phacoemulsification combined with micropulse cyclodiode laser in glaucoma patients: efficacy and safety
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581962/
https://www.ncbi.nlm.nih.gov/pubmed/34743209
http://dx.doi.org/10.1038/s41433-021-01826-1
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