Claudin-3 inhibits tumor-induced lymphangiogenesis via regulating the PI3K signaling pathway in lymphatic endothelial cells

Claudin-3 is a tight junction protein that has often been associated with the progression and metastasis of various tumors. Here, the role of claudin-3 in tumor-induced lymphangiogenesis is investigated. We found an increased lymphangiogenesis in the B16F10 tumor in claudin-3 knockout mice, accompan...

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Detalles Bibliográficos
Autores principales: Lei, Ningjing, Cheng, Yanru, Wan, Jiajia, Blasig, Rosel, Li, Anqi, Bai, Yueyue, Haseloff, Reiner F., Blasig, Ingolf E., Zhu, Linyu, Qin, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581975/
https://www.ncbi.nlm.nih.gov/pubmed/36261482
http://dx.doi.org/10.1038/s41598-022-22156-6

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