Consecutive dosing of UVB irradiation induces loss of ABCB5 expression and activation of EMT and fibrosis proteins in limbal epithelial cells similar to pterygium epithelium

Pterygium pathogenesis is often attributed to a population of altered limbal stem cells, which initiate corneal invasion and drive the hyperproliferation and fibrosis associated with the disease. These cells are thought to undergo epithelial to mesenchymal transition (EMT) and to contribute to subep...

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Detalles Bibliográficos
Autores principales: Domdey, M., Kluth, M.A., Maßlo, C., Ganss, C., Frank, M.H., Frank, N.Y., Coroneo, M.T., Cursiefen, C., Notara, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582195/
https://www.ncbi.nlm.nih.gov/pubmed/36242878
http://dx.doi.org/10.1016/j.scr.2022.102936

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