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A non-functional 5′ ALK fusion validated at the RNA level as a classical EML4-ALK that responds well to the novel ALK inhibitor ensartinib: A case report

BACKGROUND: Currently, many targeted drugs are approved for treatment of ALK fusion non-small cell lung cancer. However, it has been previously assumed that patients with 5′ non-oncogenic kinase (5′ NOK) fusion detected by DNA next-generation sequencing (NGS) would not benefit from ALK inhibitors be...

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Detalles Bibliográficos
Autores principales:	Yang, Hong, Li, Haojing, Fang, Yu, Li, Zhijun, Zhu, Jianhua, Liu, Huan, Lu, Chao, Zhang, Xiaoyan, Ma, Tonghui, Zhang, Cuiying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582288/ https://www.ncbi.nlm.nih.gov/pubmed/36275795 http://dx.doi.org/10.3389/fmed.2022.979032

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