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Preliminary study of sound touch elastography in diffuse thyroid disease in children
OBJECTIVE: The purpose of this study was to evaluate the use of sound touch elastography (STE) in conjunction with conventional ultrasound in the differential diagnosis of diffuse thyroid disease (DTD) and normal thyroid in children. METHODS: Studies performed on 62 children with DTD and 30 normal v...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582431/ https://www.ncbi.nlm.nih.gov/pubmed/36275048 http://dx.doi.org/10.3389/fped.2022.964413 |
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author | Li, Lin Zhang, Aimei Chen, Dan Taragin, Benjamin H. Luo, Xiaoyong |
author_facet | Li, Lin Zhang, Aimei Chen, Dan Taragin, Benjamin H. Luo, Xiaoyong |
author_sort | Li, Lin |
collection | PubMed |
description | OBJECTIVE: The purpose of this study was to evaluate the use of sound touch elastography (STE) in conjunction with conventional ultrasound in the differential diagnosis of diffuse thyroid disease (DTD) and normal thyroid in children. METHODS: Studies performed on 62 children with DTD and 30 normal volunteers were reviewed. Standard gray scale ultrasound, Doppler ultrasound and STE of the examinees, and the serum test results of children with DTD were collected, analyzed and compared. RESULTS: The STE-Mean values in the Graves’ disease (GD) group, Hashimoto’s thyroiditis (HT) group, and normal control group, respectively, were 19.35 ± 5.00 kPa, 19.43 ± 6.06 kPa, and 11.24 ± 1.99 kPa. With an area under the ROC curve (AUC) of 0.945, STE-Mean values differentiated DTD from normal children. The peak systolic velocity (PSV) of the superior thyroid artery separated DTD from normal children and AUC from children with GD and HT, respectively, and was 0.992 and 0.864. The PSV of superior thyroid artery revealed a somewhat favorable connection with FT3 and FT4. CONCLUSION: The STE results revealed that thyroid stiffness was higher in children with DTD than in normal children, but further differentiation into GD and HT subgroups lacked specificity, and the superior thyroid artery flow velocity might be a good supplement to distinguish both. |
format | Online Article Text |
id | pubmed-9582431 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95824312022-10-21 Preliminary study of sound touch elastography in diffuse thyroid disease in children Li, Lin Zhang, Aimei Chen, Dan Taragin, Benjamin H. Luo, Xiaoyong Front Pediatr Pediatrics OBJECTIVE: The purpose of this study was to evaluate the use of sound touch elastography (STE) in conjunction with conventional ultrasound in the differential diagnosis of diffuse thyroid disease (DTD) and normal thyroid in children. METHODS: Studies performed on 62 children with DTD and 30 normal volunteers were reviewed. Standard gray scale ultrasound, Doppler ultrasound and STE of the examinees, and the serum test results of children with DTD were collected, analyzed and compared. RESULTS: The STE-Mean values in the Graves’ disease (GD) group, Hashimoto’s thyroiditis (HT) group, and normal control group, respectively, were 19.35 ± 5.00 kPa, 19.43 ± 6.06 kPa, and 11.24 ± 1.99 kPa. With an area under the ROC curve (AUC) of 0.945, STE-Mean values differentiated DTD from normal children. The peak systolic velocity (PSV) of the superior thyroid artery separated DTD from normal children and AUC from children with GD and HT, respectively, and was 0.992 and 0.864. The PSV of superior thyroid artery revealed a somewhat favorable connection with FT3 and FT4. CONCLUSION: The STE results revealed that thyroid stiffness was higher in children with DTD than in normal children, but further differentiation into GD and HT subgroups lacked specificity, and the superior thyroid artery flow velocity might be a good supplement to distinguish both. Frontiers Media S.A. 2022-10-06 /pmc/articles/PMC9582431/ /pubmed/36275048 http://dx.doi.org/10.3389/fped.2022.964413 Text en Copyright © 2022 Li, Zhang, Chen, Taragin and Luo. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pediatrics Li, Lin Zhang, Aimei Chen, Dan Taragin, Benjamin H. Luo, Xiaoyong Preliminary study of sound touch elastography in diffuse thyroid disease in children |
title | Preliminary study of sound touch elastography in diffuse thyroid disease in children |
title_full | Preliminary study of sound touch elastography in diffuse thyroid disease in children |
title_fullStr | Preliminary study of sound touch elastography in diffuse thyroid disease in children |
title_full_unstemmed | Preliminary study of sound touch elastography in diffuse thyroid disease in children |
title_short | Preliminary study of sound touch elastography in diffuse thyroid disease in children |
title_sort | preliminary study of sound touch elastography in diffuse thyroid disease in children |
topic | Pediatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582431/ https://www.ncbi.nlm.nih.gov/pubmed/36275048 http://dx.doi.org/10.3389/fped.2022.964413 |
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