Cargando…

Novel molecular mechanisms in Alzheimer’s disease: The potential role of DEK in disease pathogenesis

Alzheimer’s disease and age-related dementias (AD/ADRD) are debilitating diseases that exact a significant physical, emotional, cognitive, and financial toll on the individual and their social network. While genetic risk factors for early-onset AD have been identified, the molecular and genetic driv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Greene, Allie N., Solomon, Matia B., Privette Vinnedge, Lisa M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582447/ https://www.ncbi.nlm.nih.gov/pubmed/36275000 http://dx.doi.org/10.3389/fnagi.2022.1018180

Ejemplares similares

Loss of DEK Expression Induces Alzheimer’s Disease Phenotypes in Differentiated SH-SY5Y Cells
por: Greene, Allie N., et al.
Publicado: (2020)

Dissecting the Potential Interplay of DEK Functions in Inflammation and Cancer
por: Pease, Nicholas A., et al.
Publicado: (2015)

The DEK Oncogene Is a Target of Steroid Hormone Receptor Signaling in Breast Cancer
por: Privette Vinnedge, Lisa M., et al.
Publicado: (2012)

DEK Expression in Breast Cancer Cells Leads to the Alternative Activation of Tumor Associated Macrophages
por: Pease, Nicholas A., et al.
Publicado: (2020)

The human DEK oncogene stimulates beta catenin signaling, invasion and mammosphere formation in breast cancer
por: Privette Vinnedge, Lisa M., et al.
Publicado: (2011)

The DEK oncogene promotes cellular proliferation through paracrine Wnt signaling in Ron receptor positive breast cancers
por: Privette Vinnedge, Lisa M., et al.
Publicado: (2014)

DEK is required for homologous recombination repair of DNA breaks
por: Smith, Eric A., et al.
Publicado: (2017)

Microglia in Alzheimer’s disease: pathogenesis, mechanisms, and therapeutic potentials
por: Miao, Jifei, et al.
Publicado: (2023)

Decreased plasma DEK Oncogene Levels Correlate with p16-Negative Disease and Advanced Tumor Stage in a Case–Control Study of Patients with Head and Neck Squamous Cell Carcinoma
por: Wise-Draper, Trisha, et al.
Publicado: (2017)

PB2164: PROGNOSTIC IMPACT OF ONCOGENE DEK IN DIFFUSE LARGE B-CELL LYMPHOMA
por: Alonso Alonso, R., et al.
Publicado: (2022)

Molecular Mechanisms for Herpes Simplex Virus Type 1 Pathogenesis in Alzheimer’s Disease
por: Harris, Steven A., et al.
Publicado: (2018)

Tau Clearance Mechanisms and Their Possible Role in the Pathogenesis of Alzheimer Disease
por: Chesser, Adrianne S., et al.
Publicado: (2013)

TMP21 in Alzheimer’s Disease: Molecular Mechanisms and a Potential Target
por: Qiu, Kaixin, et al.
Publicado: (2019)

Role of TGFβ signaling in the pathogenesis of Alzheimer’s disease
por: von Bernhardi, Rommy, et al.
Publicado: (2015)

The Eminent Role of microRNAs in the Pathogenesis of Alzheimer's Disease
por: Samadian, Mohammad, et al.
Publicado: (2021)

Roles of eIF2α kinases in the pathogenesis of Alzheimer’s disease
por: Ohno, Masuo
Publicado: (2014)

The Role of Exosomes as Mediators of Neuroinflammation in the Pathogenesis and Treatment of Alzheimer’s Disease
por: Weng, Shiting, et al.
Publicado: (2022)

Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer’s Disease
por: Marttinen, Mikael, et al.
Publicado: (2018)

Inflamma-MicroRNAs in Alzheimer’s Disease: From Disease Pathogenesis to Therapeutic Potentials
por: Liang, Yuanyuan, et al.
Publicado: (2021)

Drug resistance mechanisms create targetable proteostatic vulnerabilities in Her2+ breast cancers
por: Singh, Navneet, et al.
Publicado: (2022)

Histone Acetylation Modifiers in the Pathogenesis of Alzheimer’s Disease
por: Lu, Xi, et al.
Publicado: (2015)

Modifications and Trafficking of APP in the Pathogenesis of Alzheimer’s Disease
por: Wang, Xin, et al.
Publicado: (2017)

Circulating extracellular vesicle-containing microRNAs reveal potential pathogenesis of Alzheimer’s disease
por: Wang, Yi, et al.
Publicado: (2022)

Role of endoplasmic reticulum Ca2+ signaling in the pathogenesis of Alzheimer disease
por: Popugaeva, Elena, et al.
Publicado: (2013)

Exploring the role of sex differences in Alzheimer's disease pathogenesis in Down syndrome
por: Andrews, Elizabeth J., et al.
Publicado: (2022)

Neuroinflammation in the pathogenesis of Alzheimer’s disease. A rational framework for the search of novel therapeutic approaches
por: Morales, Inelia, et al.
Publicado: (2014)

Co-expression Network Analysis Reveals Novel Genes Underlying Alzheimer’s Disease Pathogenesis
por: Hu, Rui-ting, et al.
Publicado: (2020)

The Role of Iron-Induced Fibrin in the Pathogenesis of Alzheimer’s Disease and the Protective Role of Magnesium
por: Lipinski, Boguslaw, et al.
Publicado: (2013)

Iron and Alzheimer’s Disease: From Pathogenesis to Therapeutic Implications
por: Liu, Jun-Lin, et al.
Publicado: (2018)

Dysfunctional Mitochondria and Mitophagy as Drivers of Alzheimer’s Disease Pathogenesis
por: Chakravorty, Anushka, et al.
Publicado: (2019)

Most Pathways Can Be Related to the Pathogenesis of Alzheimer’s Disease
por: Morgan, Sarah L., et al.
Publicado: (2022)

Roles of Selenoproteins in Brain Function and the Potential Mechanism of Selenium in Alzheimer’s Disease
por: Zhang, Zhong-Hao, et al.
Publicado: (2021)

Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer’s disease
por: Guo, Tiantian, et al.
Publicado: (2020)

Connectivity of Pathology: The Olfactory System as a Model for Network-Driven Mechanisms of Alzheimer’s Disease Pathogenesis
por: Franks, Katherine H., et al.
Publicado: (2015)

The Role of Chronic Inflammatory Bone and Joint Disorders in the Pathogenesis and Progression of Alzheimer's Disease
por: Culibrk, Robert A., et al.
Publicado: (2020)

Autophagy and Alzheimer’s Disease: From Molecular Mechanisms to Therapeutic Implications
por: Uddin, Md. Sahab, et al.
Publicado: (2018)

The Fourth Element Targeting Hypothesis of Alzheimer's Disease Pathogenesis and Pathophysiology
por: Kuljiš, Rodrigo O.
Publicado: (2010)

Molecular Chaperone Accumulation in Cancer and Decrease in Alzheimer's Disease: The Potential Roles of HSF1
por: Calderwood, Stuart K., et al.
Publicado: (2017)

Alzheimer Disease Pathogenesis: Insights From Molecular and Cellular Biology Studies of Oligomeric Aβ and Tau Species
por: Chen, Xu-Qiao, et al.
Publicado: (2019)

Role of miR-211 in Neuronal Differentiation and Viability: Implications to Pathogenesis of Alzheimer’s Disease
por: Fan, Chunying, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_jvfmg1jfteual6ictek2qkhpca