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Platelets upregulate tumor cell programmed death ligand 1 in an epidermal growth factor receptor-dependent manner in vitro

Programmed death ligand 1 (PD-L1) is an immune checkpoint protein that suppresses cytotoxic T lymphocytes and is often overexpressed in cancers. Due to favorable clinical trial results, immune checkpoint inhibition (ICI) is part of Food and Drug Administration approved immuno-oncology therapies; how...

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Detalles Bibliográficos
Autores principales:	Guo, Qiuchen, Malloy, Michael W., Roweth, Harvey G., McAllister, Sandra S., Italiano, Joseph E., Battinelli, Elisabeth M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society of Hematology 2022
Materias:	Stimulus Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582587/ https://www.ncbi.nlm.nih.gov/pubmed/35482455 http://dx.doi.org/10.1182/bloodadvances.2021006120

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