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Molecular basis underlying the ciliary defects caused by IFT52 variations found in skeletal ciliopathies

Bidirectional protein trafficking within cilia is mediated by the intraflagellar transport (IFT) machinery, which contains the IFT-A and IFT-B complexes powered by the kinesin-2 and dynein-2 motors. Mutations in genes encoding subunits of the IFT-A and dynein-2 complexes cause skeletal ciliopathies....

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Detalles Bibliográficos
Autores principales:	Ishida, Yamato, Tasaki, Koshi, Katoh, Yohei, Nakayama, Kazuhisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582644/ https://www.ncbi.nlm.nih.gov/pubmed/35704471 http://dx.doi.org/10.1091/mbc.E22-05-0188

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