Salt-inducible kinase 1 deficiency promotes vascular remodeling in pulmonary arterial hypertension via enhancement of yes-associated protein-mediated proliferation

Pulmonary arterial remodeling at an early stage, including excessive proliferation and migration of smooth muscle cells, is a hallmark of pulmonary arterial hypertension (PAH). Salt-inducible kinases (SIKs) have been increasingly reported to play a key role in smooth muscle cell proliferation and ph...

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Detalles Bibliográficos
Autores principales: Pu, Jiangqin, Wang, Feng, Ye, Peng, Jiang, Xiaomin, Zhou, Wenying, Gu, Yue, Chen, Shaoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582722/
https://www.ncbi.nlm.nih.gov/pubmed/36276742
http://dx.doi.org/10.1016/j.heliyon.2022.e11016

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