Synthesis and biological evaluation of novel sinomenine derivatives as anti-inflammatory and analgesic agent

Sinomenine (SIN) has long been known as an anti-inflammatory drug, while poor efficiency and large-dose treatment had limited its further application. A series of novel SIN derivatives 1–26 were designed and synthesized to improve its anti-inflammatory activity. The anti-inflammatory activity evalua...

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Detalles Bibliográficos
Autores principales: Gao, Feng, Dai, Ziqi, Zhang, Tong, Gu, Yuhao, Cai, Desheng, Lu, Mingjun, Zhang, Zijie, Zeng, Qi, Shang, Bingxian, Xu, Bing, Lei, Haimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582731/
https://www.ncbi.nlm.nih.gov/pubmed/36321084
http://dx.doi.org/10.1039/d2ra05558a

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