Integrative analysis of macrophage ribo-Seq and RNA-Seq data define glucocorticoid receptor regulated inflammatory response genes into distinct regulatory classes

Glucocorticoids such as dexamethasone (Dex) are widely used to treat both acute and chronic inflammatory conditions. They regulate immune responses by dampening cell-mediated immunity in a glucocorticoid receptor (GR)-dependent manner, by suppressing the expression of pro-inflammatory cytokines and...

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Detalles Bibliográficos
Autores principales: Ansari, Suhail A., Dantoft, Widad, Ruiz-Orera, Jorge, Syed, Afzal P., Blachut, Susanne, van Heesch, Sebastiaan, Hübner, Norbert, Uhlenhaut, Nina Henriette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582734/
https://www.ncbi.nlm.nih.gov/pubmed/36284713
http://dx.doi.org/10.1016/j.csbj.2022.09.042

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