Big dynorphin is a neuroprotector scaffold against amyloid β-peptide aggregation and cell toxicity

Amyloid β-peptide (Aβ) misfolding into β-sheet structures triggers neurotoxicity inducing Alzheimer’s disease (AD). Molecules able to reduce or to impair Aβ aggregation are highly relevant as possible AD treatments since they should protect against Aβ neurotoxicity. We have studied the effects of th...

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Detalles Bibliográficos
Autores principales: Gallego-Villarejo, Lucía, Wallin, Cecilia, Król, Sylwia, Enrich-Bengoa, Jennifer, Suades, Albert, Aguilella-Arzo, Marcel, Gomara, María José, Haro, Isabel, Wärmlander, Sebastian, Muñoz, Francisco J., Gräslund, Astrid, Perálvarez-Marín, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Special Issue articles from "Peptide structural conversions and cross-interactions in health and disease" edited by Alex Perálvarez-Marín
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582793/
https://www.ncbi.nlm.nih.gov/pubmed/36284704
http://dx.doi.org/10.1016/j.csbj.2022.10.014

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