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Extracellular matrix regulates force transduction at VE-cadherin junctions

Increased tension on VE-cadherin (VE-cad) complexes activates adaptive cell stiffening and local cytoskeletal reinforcement–-two key signatures of intercellular mechanotransduction. Here we demonstrate that tugging on VE-cad receptors initiates a cascade that results in downstream integrin activatio...

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Detalles Bibliográficos
Autores principales:	Kong, Xinyu, Kapustka, Adrian, Sullivan, Brendan, Schwarz, Gregory J., Leckband, Deborah E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582804/ https://www.ncbi.nlm.nih.gov/pubmed/35653290 http://dx.doi.org/10.1091/mbc.E22-03-0075

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