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LPS activates neuroinflammatory pathways to induce depression in Parkinson’s disease-like condition

Aim: This study aimed to observe the effects of lipopolysaccharide (LPS) intraperitoneal (i.p.) injection on rats and investigate how neuroinflammation contributes to the pathogenesis of depression in Parkinson’s disease (dPD). Methods: Rats were administered LPS (0.5 mg/kg, i.p.) for either 1, 2, o...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Xue, Bing, Jing, Bin, Tian, Huiling, Zhang, Naiwen, Li, Mengyuan, Lu, Lihua, Chen, Lin, Diao, Huaqiong, Chen, Yufei, Wang, Min, Li, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582846/
https://www.ncbi.nlm.nih.gov/pubmed/36278237
http://dx.doi.org/10.3389/fphar.2022.961817