Cargando…

The hexosamine biosynthesis pathway-related gene signature correlates with immune infiltration and predicts prognosis of patients with osteosarcoma

OBJECTIVES: Osteosarcoma is a malignant bone tumor with poor outcomes affecting the adolescents and elderly. In this study, we comprehensively assessed the metabolic characteristics of osteosarcoma patients and constructed a hexosamine biosynthesis pathway (HBP)-based risk score model to predict the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Su, Zexin, Wang, Chenyang, Pan, Runsang, Li, Hongbo, Chen, Junkai, Tan, Jianye, Tian, Xiaobin, Lin, Tiao, Shen, Jingnan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582954/ https://www.ncbi.nlm.nih.gov/pubmed/36275679 http://dx.doi.org/10.3389/fimmu.2022.1028263

Ejemplares similares

A novel immune cell signature for predicting osteosarcoma prognosis and guiding therapy
por: Pan, Runsang, et al.
Publicado: (2022)

A glycometabolic gene signature associating with immune infiltration and chemosensitivity and predicting the prognosis of patients with osteosarcoma
por: Wang, Fengyan, et al.
Publicado: (2023)

Identification of hexosamine biosynthesis pathway as a novel prognostic signature and its correlation with immune infiltration in bladder cancer
por: Cui, Yangyan, et al.
Publicado: (2022)

A Disulfidptosis-Related Gene Signature Associated with Prognosis and Immune Cell Infiltration in Osteosarcoma
por: Chen, Pengyu, et al.
Publicado: (2023)

The Hexosamine Biosynthesis Pathway: Regulation and Function
por: Paneque, Alysta, et al.
Publicado: (2023)

Identification of prognostic biomarkers associated with metastasis and immune infiltration in osteosarcoma
por: Yang, Bingsheng, et al.
Publicado: (2021)

A novel molecular signature for predicting prognosis and immunotherapy response in osteosarcoma based on tumor-infiltrating cell marker genes
por: Tang, Haijun, et al.
Publicado: (2023)

Targeting a critical step in fungal hexosamine biosynthesis
por: Lockhart, Deborah E. A., et al.
Publicado: (2020)

Prognostic relevance of the hexosamine biosynthesis pathway activation in leiomyosarcoma
por: Tolwani, Angela, et al.
Publicado: (2021)

The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiae
por: Alme, Emma B., et al.
Publicado: (2020)

Molecular characterization of immunogenic cell death indicates prognosis and tumor microenvironment infiltration in osteosarcoma
por: Liu, Zhongyue, et al.
Publicado: (2022)

Chronic activation of hexosamine biosynthesis in the heart triggers pathological cardiac remodeling
por: Tran, Diem Hong, et al.
Publicado: (2020)

Current knowledge and potential intervention of hexosamine biosynthesis pathway in lung cancer
por: Zou, Yi, et al.
Publicado: (2023)

Infiltration of LPAR5(+) macrophages in osteosarcoma tumor microenvironment predicts better outcomes
por: He, Yi, et al.
Publicado: (2022)

Pyroptosis-Related Signature Predicts Prognosis and Immunotherapy Efficacy in Muscle-Invasive Bladder Cancer
por: Zhang, Qi, et al.
Publicado: (2022)

Identification of an Immune Signature Predicting Prognosis Risk and Lymphocyte Infiltration in Colon Cancer
por: Li, Xinyu, et al.
Publicado: (2020)

A novel signature to guide osteosarcoma prognosis and immune microenvironment: Cuproptosis-related lncRNA
por: Yang, Mingyi, et al.
Publicado: (2022)

Acute Regulation of Cardiac Metabolism by the Hexosamine Biosynthesis Pathway and Protein O-GlcNAcylation
por: Laczy, Boglárka, et al.
Publicado: (2011)

Anoctamin 5 promotes osteosarcoma development by increasing degradation of Nel-like proteins 1 and 2
por: Pan, Runsang, et al.
Publicado: (2021)

Characterization of the Tumor Microenvironment in Osteosarcoma Identifies Prognostic- and Immunotherapy-Relevant Gene Signatures
por: Tan, Jianye, et al.
Publicado: (2022)

Comprehensive analysis of a glycolysis and cholesterol synthesis-related genes signature for predicting prognosis and immune landscape in osteosarcoma
por: Xu, Fangxing, et al.
Publicado: (2022)

Tumor-Infiltrated CD8+ T Cell 10-Gene Signature Related to Clear Cell Renal Cell Carcinoma Prognosis
por: Wang, Jie, et al.
Publicado: (2022)

A cuproptosis-related genes signature associated with prognosis and immune cell infiltration in osteosarcoma
por: Yang, Weiguang, et al.
Publicado: (2022)

Hexosamine Biosynthesis Is a Possible Mechanism Underlying Hypoxia’s Effects on Lipid Metabolism in Human Adipocytes
por: O’Rourke, Robert W., et al.
Publicado: (2013)

The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1-mutant lung cancer
por: Kim, Jiyeon, et al.
Publicado: (2020)

Construction and Validation of an Immune Infiltration-Related Gene Signature for the Prediction of Prognosis and Therapeutic Response in Breast Cancer
por: Peng, Yang, et al.
Publicado: (2021)

The cancer-associated fibroblast-related signature predicts prognosis and indicates immune microenvironment infiltration in gastric cancer
por: Mak, Tsz Kin, et al.
Publicado: (2022)

KCNJ2/HIF1α positive-feedback loop promotes the metastasis of osteosarcoma
por: Shen, Mao, et al.
Publicado: (2023)

An Immune-Related Signature for Predicting the Prognosis of Lower-Grade Gliomas
por: Zhang, Hongbo, et al.
Publicado: (2020)

Comprehensive Analysis of Myeloid Signature Genes in Head and Neck Squamous Cell Carcinoma to Predict the Prognosis and Immune Infiltration
por: Liu, Zhifeng, et al.
Publicado: (2021)

First characterization of glucose flux through the hexosamine biosynthesis pathway (HBP) in ex vivo mouse heart
por: Olson, Aaron K., et al.
Publicado: (2020)

Dietary glucosamine overcomes the defects in αβ-T cell ontogeny caused by the loss of de novo hexosamine biosynthesis
por: Werlen, Guy, et al.
Publicado: (2022)

PDIA5 is Correlated With Immune Infiltration and Predicts Poor Prognosis in Gliomas
por: Zhang, Hao, et al.
Publicado: (2021)

Development of a Novel Immune Infiltration-Based Gene Signature to Predict Prognosis and Immunotherapy Response of Patients With Cervical Cancer
por: Yu, Sihui, et al.
Publicado: (2021)

Based on disulfidptosis-related glycolytic genes to construct a signature for predicting prognosis and immune infiltration analysis of hepatocellular carcinoma
por: Wang, Zhijian, et al.
Publicado: (2023)

Identification and experimental validation of a tumor-infiltrating lymphocytes–related long noncoding RNA signature for prognosis of clear cell renal cell carcinoma
por: Deng, Yulin, et al.
Publicado: (2022)

Vessel state and immune infiltration of the angiogenesis subgroup and construction of a prediction model in osteosarcoma
por: Wu, Jintao, et al.
Publicado: (2022)

Construction and experimental validation of a signature for predicting prognosis and immune infiltration analysis of glioma based on disulfidptosis-related lncRNAs
por: Guo, Youwei, et al.
Publicado: (2023)

Comprehensive analysis of nicotinamide metabolism-related signature for predicting prognosis and immunotherapy response in breast cancer
por: Cui, Hanxiao, et al.
Publicado: (2023)

Glutamine is a substrate for glycosylation and CA19-9 biosynthesis through hexosamine biosynthetic pathway in pancreatic cancer
por: Liu, Chen, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_54em009877c80va4cu0qig9uoo