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Anti-fibrotic effect of extracellular vesicles derived from tea leaves in hepatic stellate cells and liver fibrosis mice

BACKGROUND: Activation of hepatic stellate cells (HSCs) is essential for the pathogenesis of liver fibrosis, there is no effective drug used to prevent or reverse the fibrotic process. METHODS: With human hepatic stellate cell line LX-2 and mouse model of CCl(4)-induced liver fibrosis, we investigat...

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Detalles Bibliográficos
Autores principales: Gong, Qianyuan, Zeng, Zhaoyu, Jiang, Tao, Bai, Xue, Pu, Chunlan, Hao, Yaying, Guo, Yuanbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582986/
https://www.ncbi.nlm.nih.gov/pubmed/36276815
http://dx.doi.org/10.3389/fnut.2022.1009139