New mechanistic insights into the RAS-SIN1 interaction at the membrane

Stress-activated MAP kinase-interacting protein 1 (SIN1) is a central member of the mTORC2 complex that contains an N-terminal domain (NTD), a conserved region in the middle (CRIM), a RAS-binding domain (RBD), and a pleckstrin homology domain. Recent studies provided valuable structural and function...

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Detalles Bibliográficos
Autores principales: Pudewell, Silke, Lissy, Jana, Nakhaeizadeh, Hossein, Mosaddeghzadeh, Niloufar, Nakhaei-Rad, Saeideh, Dvorsky, Radovan, Ahmadian, Mohammad R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583166/
https://www.ncbi.nlm.nih.gov/pubmed/36274845
http://dx.doi.org/10.3389/fcell.2022.987754

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