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Transmembrane domain of IFITM3 is responsible for its interaction with influenza virus HA(2) subunit

Interferon-inducible transmembrane protein 3 (IFITM3) inhibits influenza virus infection by blocking viral membrane fusion, but the exact mechanism remains elusive. Here, we investigated the function and key region of IFITM3 in blocking influenza virus entry mediated by hemagglutinin (HA). The restr...

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Detalles Bibliográficos
Autores principales: Xu, Wang, Wang, Yuhang, Li, Letian, Qu, Xiaoyun, Liu, Quan, Li, Tiyuan, Wu, Shipin, Liao, Ming, Jin, Ningyi, Du, Shouwen, Li, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583175/
https://www.ncbi.nlm.nih.gov/pubmed/35809785
http://dx.doi.org/10.1016/j.virs.2022.07.002