H7N9 bearing a mutation in the nucleoprotein leads to increased pathology in chickens

The zoonotic H7N9 avian influenza (AI) virus first emerged in 2013 as a low pathogenic (LPAI) strain, and has repeatedly caused human infection resulting in severe respiratory illness and a mortality of ~39% (>600 deaths) across five epidemic waves. This virus has circulated in poultry with littl...

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Detalles Bibliográficos
Autores principales: Layton, Daniel S., Butler, Jeffrey, Stewart, Cameron, Stevens, Vicky, Payne, Jean, Rootes, Christina, Deffrasnes, Celine, Walker, Som, Shan, Songhua, Gough, Tamara J., Cowled, Christopher, Bruce, Kerri, Wang, Jianning, Kedzierska, Katherine, Wong, Frank Y. K., Bean, Andrew G. D., Bingham, John, Williams, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583263/
https://www.ncbi.nlm.nih.gov/pubmed/36275684
http://dx.doi.org/10.3389/fimmu.2022.974210

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