Quinazoline-4(3H)-one-7-carboxamide Derivatives as Human Soluble Epoxide Hydrolase Inhibitors with Developable 5-Lipoxygenase Activating Protein Inhibition

[Image: see text] Soluble epoxide hydrolase (sEH) metabolizes epoxyeicosatrienoic acids (EETs), which are endowed with beneficial biological activities as they reduce inflammation, regulate endothelial tone, improve mitochondrial function, and decrease oxidative stress. Therefore, inhibition of sEH...

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Detalles Bibliográficos
Autores principales: Turanlı, Sümeyye, Ergül, Azize Gizem, Jordan, Paul M., Olğaç, Abdurrahman, Çalışkan, Burcu, Werz, Oliver, Banoglu, Erden
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583330/
https://www.ncbi.nlm.nih.gov/pubmed/36278102
http://dx.doi.org/10.1021/acsomega.2c04039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583330/
https://www.ncbi.nlm.nih.gov/pubmed/36278102
http://dx.doi.org/10.1021/acsomega.2c04039

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