Bet v 1-displaying elastin-like polypeptide nanoparticles induce a strong humoral and weak CD4+ T-cell response against Bet v 1 in a murine immunogenicity model

There is growing concern about the toxicity of colloidal aluminum salts used as adjuvants in subcutaneous allergen immunotherapy (SCIT). Therefore, alternative adjuvants and delivery systems are being explored to replace alum in SCIT. We applied micellar elastin-like polypeptides (ELPs), a type of s...

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Detalles Bibliográficos
Autores principales: van Strien, Jolinde, Warmenhoven, Hans, Logiantara, Adrian, Makurat, Max, Aglas, Lorenz, Bethanis, Athanasios, Leboux, Romain, van Rijt, Leonie, MacKay, J. Andrew, van Schijndel, Johannes W., Schneider, Gregory, Olsthoorn, René, Jiskoot, Wim, van Ree, Ronald, Kros, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583423/
https://www.ncbi.nlm.nih.gov/pubmed/36275650
http://dx.doi.org/10.3389/fimmu.2022.1006776

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