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Computational quantification and characterization of independently evolving cellular subpopulations within tumors is critical to inhibit anti-cancer therapy resistance

BACKGROUND: Drug resistance continues to be a major limiting factor across diverse anti-cancer therapies. Contributing to the complexity of this challenge is cancer plasticity, in which one cancer subtype switches to another in response to treatment, for example, triple-negative breast cancer (TNBC)...

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Detalles Bibliográficos
Autores principales:	Alkhatib, Heba, Rubinstein, Ariel M., Vasudevan, Swetha, Flashner-Abramson, Efrat, Stefansky, Shira, Chowdhury, Sangita Roy, Oguche, Solomon, Peretz-Yablonsky, Tamar, Granit, Avital, Granot, Zvi, Ben-Porath, Ittai, Sheva, Kim, Feldman, Jon, Cohen, Noa E., Meirovitz, Amichay, Kravchenko-Balasha, Nataly
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583500/ https://www.ncbi.nlm.nih.gov/pubmed/36266692 http://dx.doi.org/10.1186/s13073-022-01121-y

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