Aptamer‐Based Cancer Cell Analysis and Treatment

Aptamers are a class of single‐stranded DNA or RNA oligonucleotides that can exclusively bind to various targets with high affinity and selectivity. Regarded as “chemical antibodies”, aptamers possess several intrinsic advantages, including easy synthesis, convenient modification, high programmabili...

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Detalles Bibliográficos
Autores principales: Wu, Limei, Zhang, Yutong, Wang, Zhimin, Zhang, Yue, Zou, Jianmei, Qiu, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583543/
https://www.ncbi.nlm.nih.gov/pubmed/36264016
http://dx.doi.org/10.1002/open.202200141
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author Wu, Limei
Zhang, Yutong
Wang, Zhimin
Zhang, Yue
Zou, Jianmei
Qiu, Liping
author_facet Wu, Limei
Zhang, Yutong
Wang, Zhimin
Zhang, Yue
Zou, Jianmei
Qiu, Liping
author_sort Wu, Limei
collection PubMed
description Aptamers are a class of single‐stranded DNA or RNA oligonucleotides that can exclusively bind to various targets with high affinity and selectivity. Regarded as “chemical antibodies”, aptamers possess several intrinsic advantages, including easy synthesis, convenient modification, high programmability, and good biocompatibility. In recent decades, many studies have demonstrated the superiority of aptamers as molecular tools for various biological applications, particularly in the area of cancer theranostics. In this review, we focus on recent progress in developing aptamer‐based strategies for the precise analysis and treatment of cancer cells.
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spelling pubmed-95835432022-10-21 Aptamer‐Based Cancer Cell Analysis and Treatment Wu, Limei Zhang, Yutong Wang, Zhimin Zhang, Yue Zou, Jianmei Qiu, Liping ChemistryOpen Reviews Aptamers are a class of single‐stranded DNA or RNA oligonucleotides that can exclusively bind to various targets with high affinity and selectivity. Regarded as “chemical antibodies”, aptamers possess several intrinsic advantages, including easy synthesis, convenient modification, high programmability, and good biocompatibility. In recent decades, many studies have demonstrated the superiority of aptamers as molecular tools for various biological applications, particularly in the area of cancer theranostics. In this review, we focus on recent progress in developing aptamer‐based strategies for the precise analysis and treatment of cancer cells. John Wiley and Sons Inc. 2022-10-20 /pmc/articles/PMC9583543/ /pubmed/36264016 http://dx.doi.org/10.1002/open.202200141 Text en © 2022 The Authors. Published by Wiley-VCH GmbH https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Reviews
Wu, Limei
Zhang, Yutong
Wang, Zhimin
Zhang, Yue
Zou, Jianmei
Qiu, Liping
Aptamer‐Based Cancer Cell Analysis and Treatment
title Aptamer‐Based Cancer Cell Analysis and Treatment
title_full Aptamer‐Based Cancer Cell Analysis and Treatment
title_fullStr Aptamer‐Based Cancer Cell Analysis and Treatment
title_full_unstemmed Aptamer‐Based Cancer Cell Analysis and Treatment
title_short Aptamer‐Based Cancer Cell Analysis and Treatment
title_sort aptamer‐based cancer cell analysis and treatment
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583543/
https://www.ncbi.nlm.nih.gov/pubmed/36264016
http://dx.doi.org/10.1002/open.202200141
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AT zoujianmei aptamerbasedcancercellanalysisandtreatment
AT qiuliping aptamerbasedcancercellanalysisandtreatment

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