ISGylation is induced in neurons by demyelination driving ISG15-dependent microglial activation

The causes of grey matter pathology and diffuse neuron injury in MS remain incompletely understood. Axonal stress signals arising from white matter lesions has been suggested to play a role in initiating this diffuse grey matter pathology. Therefore, to identify the most upstream transcriptional res...

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Detalles Bibliográficos
Autores principales: Clarkson, Benjamin D. S., Grund, Ethan, David, Kenneth, Johnson, Renee K., Howe, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583544/
https://www.ncbi.nlm.nih.gov/pubmed/36261842
http://dx.doi.org/10.1186/s12974-022-02618-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583544/
https://www.ncbi.nlm.nih.gov/pubmed/36261842
http://dx.doi.org/10.1186/s12974-022-02618-4

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