Cargando…
ISGylation is induced in neurons by demyelination driving ISG15-dependent microglial activation
The causes of grey matter pathology and diffuse neuron injury in MS remain incompletely understood. Axonal stress signals arising from white matter lesions has been suggested to play a role in initiating this diffuse grey matter pathology. Therefore, to identify the most upstream transcriptional res...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583544/ https://www.ncbi.nlm.nih.gov/pubmed/36261842 http://dx.doi.org/10.1186/s12974-022-02618-4 |