Cargando…
Atropisomerism in the Pharmaceutically Relevant Realm
[Image: see text] Atropisomerism is a conformational chirality that occurs when there is hindered rotation about a σ-bond. While atropisomerism is exemplified by biaryls, it is observed in many other pharmaceutically relevant scaffolds including heterobiaryls, benzamides, diarylamines, and anilides....
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583608/ https://www.ncbi.nlm.nih.gov/pubmed/36153960 http://dx.doi.org/10.1021/acs.accounts.2c00500 |