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Maintaining Myofibroblastic-Like Cancer-Associated Fibroblasts by Cancer Stemness Signal Transduction Feedback Loop

Background: Myofibroblast-like cancer-associated fibroblasts (myCAF) in the tumor microenvironment (TME) promote cancer stemness, growth, and metastasis. Cancer cell-derived osteopontin (OPN) has been reported as a biomarker related to malignant cancer growth. In this study, we confirm that cancer c...

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Detalles Bibliográficos
Autores principales: Rogers, Michael P, Kothari, Anai, Read, Meagan, Kuo, Paul C, Mi, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583706/
https://www.ncbi.nlm.nih.gov/pubmed/36284815
http://dx.doi.org/10.7759/cureus.29354