Small-molecule Wnt inhibitors are a potential novel therapy for intestinal fibrosis in Crohns disease

Intestinal fibrosis and stricture formation is an aggressive complication of Crohns disease (CD), linked to increased morbidity and costs. The present study investigates the contribution of Wingless-Int-1 (Wnt) signalling to intestinal fibrogenesis, considers potential cross-talk between Wnt and tra...

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Detalles Bibliográficos
Autores principales: Lewis, Amy, Sánchez, Saray, Berti, Giulio, Pan-Castillo, Belen, Nijhuis, Anke, Mehta, Shameer, Eleid, Liliane, Gordon, Hannah, Gadhok, Radha, Kimberley, Christopher, Minicozzi, Annamaria, Chin-Aleong, Joanne, Feakins, Roger, Kypta, Robert, Lindsay, James Oliver, Silver, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Pharmacology & Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583737/
https://www.ncbi.nlm.nih.gov/pubmed/36156078
http://dx.doi.org/10.1042/CS20210889

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