ApoE isoform-dependent effects of xanthohumol on high fat diet-induced cognitive impairments and hippocampal metabolic pathways

Consumption of a high fat diet (HFD) is linked to metabolic syndrome and cognitive impairments. This is exacerbated in age-related cognitive decline (ACD) and in individuals with a genetic risk for Alzheimer’s disease (AD). Apolipoprotein E (apoE) is involved in cholesterol metabolism. In humans, th...

Descripción completa

Detalles Bibliográficos
Autores principales: Kundu, Payel, Holden, Sarah, Paraiso, Ines L., Sudhakar, Reetesh, McQuesten, Chloe, Choi, Jaewoo, Miranda, Cristobal L., Maier, Claudia S., Bobe, Gerd, Stevens, Jan F., Raber, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583926/
https://www.ncbi.nlm.nih.gov/pubmed/36278228
http://dx.doi.org/10.3389/fphar.2022.954980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583926/
https://www.ncbi.nlm.nih.gov/pubmed/36278228
http://dx.doi.org/10.3389/fphar.2022.954980

Ejemplares similares