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ApoE isoform-dependent effects of xanthohumol on high fat diet-induced cognitive impairments and hippocampal metabolic pathways

Consumption of a high fat diet (HFD) is linked to metabolic syndrome and cognitive impairments. This is exacerbated in age-related cognitive decline (ACD) and in individuals with a genetic risk for Alzheimer’s disease (AD). Apolipoprotein E (apoE) is involved in cholesterol metabolism. In humans, th...

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Detalles Bibliográficos
Autores principales:	Kundu, Payel, Holden, Sarah, Paraiso, Ines L., Sudhakar, Reetesh, McQuesten, Chloe, Choi, Jaewoo, Miranda, Cristobal L., Maier, Claudia S., Bobe, Gerd, Stevens, Jan F., Raber, Jacob
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583926/ https://www.ncbi.nlm.nih.gov/pubmed/36278228 http://dx.doi.org/10.3389/fphar.2022.954980

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