CRISPR/Cas13a combined with hybridization chain reaction for visual detection of influenza A (H1N1) virus

This study provides proof of concept of a colorimetric biosensor for influenza H1N1 virus assay based on the CRISPR/Cas13a system and hybridization chain reaction (HCR). Target RNA of influenza H1N1 virus activated the trans-cleavage activity of Cas13a, which cleaved the special RNA sequence (-UUU-)...

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Detalles Bibliográficos
Autores principales: Zhou, Hongyu, Bu, Shengjun, Xu, Yao, Xue, Lulu, Li, Zhongyi, Hao, Zhuo, Wan, Jiayu, Tang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584272/
https://www.ncbi.nlm.nih.gov/pubmed/36264297
http://dx.doi.org/10.1007/s00216-022-04380-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584272/
https://www.ncbi.nlm.nih.gov/pubmed/36264297
http://dx.doi.org/10.1007/s00216-022-04380-1

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