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Bicarbonate defective CFTR variants increase risk for chronic pancreatitis: A meta-analysis

INTRODUCTION: Cystic fibrosis transmembrane conductance regulator (CFTR) plays a central role in pancreatic ductal fluid secretion by mediating Cl(-) and HCO(3)(-) ion transport across the apical membrane. Severe CFTR mutations that diminish chloride conductance cause cystic fibrosis (CF) if both al...

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Detalles Bibliográficos
Autores principales:	Berke, Gergő, Gede, Noémi, Szadai, Letícia, Ocskay, Klementina, Hegyi, Péter, Sahin-Tóth, Miklós, Hegyi, Eszter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584382/ https://www.ncbi.nlm.nih.gov/pubmed/36264955 http://dx.doi.org/10.1371/journal.pone.0276397

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