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Intrapulmonary shunting is a key contributor to hypoxia in COVID-19: An update on the pathophysiology

BACKGROUND: The pathophysiology of COVID-19 remains poorly understood. We aimed to estimate the contribution of intrapulmonary shunting and ventilation-to-perfusion (V(A)/Q) mismatch using a mathematical model to construct oxygen-haemoglobin dissociation curves (ODCs). METHODS: ODCs were constructed...

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Detalles Bibliográficos
Autores principales:	Mayor, Nikhil, Knights, Harry, Kotwica, Aleksandra, Coppola, Andrew Solomon Joseph, Hunter, Harriet, Jeffreys, Nathan, Morgan, Alexander, Gupta, Shivani, Prentice, James, Macfarlane, Rebecca, Russell-Jones, Emma, Dassios, Theodore, Russell-Jones, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584408/ https://www.ncbi.nlm.nih.gov/pubmed/36264932 http://dx.doi.org/10.1371/journal.pone.0273402

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