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ATP hydrolytic activity of purified Spf1p correlate with micellar lipid fluidity and is dependent on conserved residues in transmembrane helix M1

P5A ATPases are expressed in the endoplasmic reticulum (ER) of all eukaryotic cells, and their disruption results in pleiotropic phenotypes related to severe ER stress. They were recently proposed to function in peptide translocation although their specificity have yet to be confirmed in reconstitut...

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Detalles Bibliográficos
Autores principales: Ipsen, Johan Ørskov, Sørensen, Danny Mollerup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584430/
https://www.ncbi.nlm.nih.gov/pubmed/36264897
http://dx.doi.org/10.1371/journal.pone.0274908

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