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Knockout of signal peptide peptidase in the eye reduces HSV-1 replication and eye disease in ocularly infected mice
We previously reported that knocking out signal peptide peptidase (SPP), a glycoprotein K (gK) binding partner, in mouse peripheral sensory neurons reduced latency-reactivation in infected mice without affecting primary virus replication or eye disease. Since virus replication in the eye plays an es...
Autores principales: | Wang, Shaohui, Jaggi, Ujjaldeep, Ghiasi, Homayon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584536/ https://www.ncbi.nlm.nih.gov/pubmed/36215312 http://dx.doi.org/10.1371/journal.ppat.1010898 |
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