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Knockout of signal peptide peptidase in the eye reduces HSV-1 replication and eye disease in ocularly infected mice

We previously reported that knocking out signal peptide peptidase (SPP), a glycoprotein K (gK) binding partner, in mouse peripheral sensory neurons reduced latency-reactivation in infected mice without affecting primary virus replication or eye disease. Since virus replication in the eye plays an es...

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Detalles Bibliográficos
Autores principales:	Wang, Shaohui, Jaggi, Ujjaldeep, Ghiasi, Homayon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584536/ https://www.ncbi.nlm.nih.gov/pubmed/36215312 http://dx.doi.org/10.1371/journal.ppat.1010898

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