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Immunoproteasomes control activation of innate immune signaling and microglial function

Microglia are the resident immune cells of the central nervous system (CNS) and play a major role in the regulation of brain homeostasis. To maintain their cellular protein homeostasis, microglia express standard proteasomes and immunoproteasomes (IP), a proteasome isoform that preserves protein hom...

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Detalles Bibliográficos
Autores principales: Çetin, Gonca, Studencka-Turski, Maja, Venz, Simone, Schormann, Eileen, Junker, Heike, Hammer, Elke, Völker, Uwe, Ebstein, Frédéric, Krüger, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584546/
https://www.ncbi.nlm.nih.gov/pubmed/36275769
http://dx.doi.org/10.3389/fimmu.2022.982786

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