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Evidence for selection on SARS-CoV-2 RNA translation revealed by the evolutionary dynamics of mutations in UTRs and CDSs

RNA translation is the rate-limiting step when cells synthesize proteins. Elevating translation efficiency (TE) is intuitively beneficial. Particularly, when viruses invade host cells, how to compete with endogenous RNAs for efficient translation is a major issue to be resolved. We collected million...

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Detalles Bibliográficos
Autores principales: Zhu, Lin, Wang, Qi, Zhang, Weiyu, Hu, Hao, Xu, Kexin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584556/
https://www.ncbi.nlm.nih.gov/pubmed/35762570
http://dx.doi.org/10.1080/15476286.2022.2092351