Human WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation

Metastatic breast cancer remains a major cause of cancer-related deaths in women, and there are few effective therapies against this advanced disease. Emerging evidence suggests that key steps of tumor progression and metastasis are controlled by reversible epigenetic mechanisms. Using an in vivo ge...

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Detalles Bibliográficos
Autores principales: Cai, Wesley L, Chen, Jocelyn Fang-Yi, Chen, Huacui, Wingrove, Emily, Kurley, Sarah J, Chan, Lok Hei, Zhang, Meiling, Arnal-Estape, Anna, Zhao, Minghui, Balabaki, Amer, Li, Wenxue, Yu, Xufen, Krop, Ethan D, Dou, Yali, Liu, Yansheng, Jin, Jian, Westbrook, Thomas F, Nguyen, Don X, Yan, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584608/
https://www.ncbi.nlm.nih.gov/pubmed/36043466
http://dx.doi.org/10.7554/eLife.78163

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