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Small fragments of hyaluronan are increased in individuals with obesity and contribute to low-grade inflammation through TLR-mediated activation of innate immune cells
BACKGROUND AND AIM: Extracellular matrix (ECM) components released during excessive fat mass expansion are considered potential endogenous danger/alarm signals contributing to innate immune system activation. The aim of the current study was to specifically measure plasma levels of low molecular wei...
Autores principales: | Romo, Mònica, López-Vicario, Cristina, Pérez-Romero, Noelia, Casulleras, Mireia, Martínez-Puchol, Ana Isabel, Sánchez, Belén, Flores-Costa, Roger, Alcaraz-Quiles, José, Duran-Güell, Marta, Ibarzábal, Ainitze, Espert, Juan José, Clària, Joan, Titos, Esther |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584819/ https://www.ncbi.nlm.nih.gov/pubmed/35896710 http://dx.doi.org/10.1038/s41366-022-01187-z |
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