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Estimating intervention effects on infectious disease control: The effect of community mobility reduction on Coronavirus spread
Understanding the effects of interventions, such as restrictions on community and large group gatherings, is critical to controlling the spread of COVID-19. Susceptible–Infectious–Recovered (SIR) models are traditionally used to forecast the infection rates but do not provide insights into the causa...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584839/ https://www.ncbi.nlm.nih.gov/pubmed/36284923 http://dx.doi.org/10.1016/j.spasta.2022.100711 |
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author | Giffin, Andrew Gong, Wenlong Majumder, Suman Rappold, Ana G. Reich, Brian J. Yang, Shu |
author_facet | Giffin, Andrew Gong, Wenlong Majumder, Suman Rappold, Ana G. Reich, Brian J. Yang, Shu |
author_sort | Giffin, Andrew |
collection | PubMed |
description | Understanding the effects of interventions, such as restrictions on community and large group gatherings, is critical to controlling the spread of COVID-19. Susceptible–Infectious–Recovered (SIR) models are traditionally used to forecast the infection rates but do not provide insights into the causal effects of interventions. We propose a spatiotemporal model that estimates the causal effect of changes in community mobility (intervention) on infection rates. Using an approximation to the SIR model and incorporating spatiotemporal dependence, the proposed model estimates a direct and indirect (spillover) effect of intervention. Under an interference and treatment ignorability assumption, this model is able to estimate causal intervention effects, and additionally allows for spatial interference between locations. Reductions in community mobility were measured by cell phone movement data. The results suggest that the reductions in mobility decrease Coronavirus cases 4 to 7 weeks after the intervention. |
format | Online Article Text |
id | pubmed-9584839 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier B.V |
record_format | MEDLINE/PubMed |
spelling | pubmed-95848392022-10-21 Estimating intervention effects on infectious disease control: The effect of community mobility reduction on Coronavirus spread Giffin, Andrew Gong, Wenlong Majumder, Suman Rappold, Ana G. Reich, Brian J. Yang, Shu Spat Stat Article Understanding the effects of interventions, such as restrictions on community and large group gatherings, is critical to controlling the spread of COVID-19. Susceptible–Infectious–Recovered (SIR) models are traditionally used to forecast the infection rates but do not provide insights into the causal effects of interventions. We propose a spatiotemporal model that estimates the causal effect of changes in community mobility (intervention) on infection rates. Using an approximation to the SIR model and incorporating spatiotemporal dependence, the proposed model estimates a direct and indirect (spillover) effect of intervention. Under an interference and treatment ignorability assumption, this model is able to estimate causal intervention effects, and additionally allows for spatial interference between locations. Reductions in community mobility were measured by cell phone movement data. The results suggest that the reductions in mobility decrease Coronavirus cases 4 to 7 weeks after the intervention. Elsevier B.V 2022-12 2022-10-21 /pmc/articles/PMC9584839/ /pubmed/36284923 http://dx.doi.org/10.1016/j.spasta.2022.100711 Text en Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Giffin, Andrew Gong, Wenlong Majumder, Suman Rappold, Ana G. Reich, Brian J. Yang, Shu Estimating intervention effects on infectious disease control: The effect of community mobility reduction on Coronavirus spread |
title | Estimating intervention effects on infectious disease control: The effect of community mobility reduction on Coronavirus spread |
title_full | Estimating intervention effects on infectious disease control: The effect of community mobility reduction on Coronavirus spread |
title_fullStr | Estimating intervention effects on infectious disease control: The effect of community mobility reduction on Coronavirus spread |
title_full_unstemmed | Estimating intervention effects on infectious disease control: The effect of community mobility reduction on Coronavirus spread |
title_short | Estimating intervention effects on infectious disease control: The effect of community mobility reduction on Coronavirus spread |
title_sort | estimating intervention effects on infectious disease control: the effect of community mobility reduction on coronavirus spread |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584839/ https://www.ncbi.nlm.nih.gov/pubmed/36284923 http://dx.doi.org/10.1016/j.spasta.2022.100711 |
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