Antigenic cartography of well-characterized human sera shows SARS-CoV-2 neutralization differences based on infection and vaccination history

The rapid emergence of SARS-CoV-2 variants challenges vaccination strategies. Here, we collected 201 serum samples from persons with a single infection or multiple vaccine exposures, or both. We measured their neutralization titers against 15 natural variants and 7 variants with engineered spike mut...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Lusvarghi, Sabrina, Subramanian, Rahul, Epsi, Nusrat J., Wang, Richard, Goguet, Emilie, Fries, Anthony C., Echegaray, Fernando, Vassell, Russell, Coggins, Si’Ana A., Richard, Stephanie A., Lindholm, David A., Mende, Katrin, Ewers, Evan C., Larson, Derek T., Colombo, Rhonda E., Colombo, Christopher J., Joseph, Janet O., Rozman, Julia S., Smith, Alfred, Lalani, Tahaniyat, Berjohn, Catherine M., Maves, Ryan C., Jones, Milissa U., Mody, Rupal, Huprikar, Nikhil, Livezey, Jeffrey, Saunders, David, Hollis-Perry, Monique, Wang, Gregory, Ganesan, Anuradha, Simons, Mark P., Broder, Christopher C., Tribble, David R., Laing, Eric D., Agan, Brian K., Burgess, Timothy H., Mitre, Edward, Pollett, Simon D., Katzelnick, Leah C., Weiss, Carol D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584854/
https://www.ncbi.nlm.nih.gov/pubmed/36356586
http://dx.doi.org/10.1016/j.chom.2022.10.012

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