Combining mass spectrometry and machine learning to discover bioactive peptides

Peptides play important roles in regulating biological processes and form the basis of a multiplicity of therapeutic drugs. To date, only about 300 peptides in human have confirmed bioactivity, although tens of thousands have been reported in the literature. The majority of these are inactive degrad...

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Detalles Bibliográficos
Autores principales: Madsen, Christian T., Refsgaard, Jan C., Teufel, Felix G., Kjærulff, Sonny K., Wang, Zhe, Meng, Guangjun, Jessen, Carsten, Heljo, Petteri, Jiang, Qunfeng, Zhao, Xin, Wu, Bo, Zhou, Xueping, Tang, Yang, Jeppesen, Jacob F., Kelstrup, Christian D., Buckley, Stephen T., Tullin, Søren, Nygaard-Jensen, Jan, Chen, Xiaoli, Zhang, Fang, Olsen, Jesper V., Han, Dan, Grønborg, Mads, de Lichtenberg, Ulrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584923/
https://www.ncbi.nlm.nih.gov/pubmed/36266275
http://dx.doi.org/10.1038/s41467-022-34031-z

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